Baclofen (brand name Spasfon, Norflex, Rophanor and others) is used to treat muscle spasms caused by certain conditions (such as multiple sclerosis, spinal cord injury/disease). It works by helping to relax the muscles. Baclofen may also be used for other conditions as determined by your doctor. Baclofen is a muscle relaxant that what is baclofen prescribed for used to relieve muscle spasms associated with multiple sclerosis, spinal cord injury/disease, or other conditions. It works by reducing nerve impulses that travel from the brain and body to muscles, which then relaxes those muscles. Baclofen is a medication used to help relieve the symptoms of nerve and muscle-related conditions. It works by helping to relax the muscles and relax the central nervous system. Baclofen belongs to a group of drugs called skeletal muscle relaxants. Baclofen is used to treat muscle spasms caused by certain conditions (such as multiple sclerosis, spinal cord injury/disease). It works by helping to relax the muscles. Baclofen can be used in combination with other medications.