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What we are now trying to explore in animal models is, could we basically use bisphosphonate to turbocharge whatever COVID-19 vaccines may come online, hopefully within a year or so. Your first tendency may be to ask what tools you can use to deliver live lectures so students don’t miss a lecture. These days, he says, there’s no "white van driving around the block" that parents can tell kids to watch out for. It turned out that macrophages actually had nothing to do with it. It suggested that maybe our findings were incorrect or our interpretation was not correct, and that actually these macrophages have the opposite function of what we had seen and what we had published. But they kill off the macrophages, which lets you study the function of these cells in various disease models. They all have in common that they stimulate sensors in immune cells that are usually triggered by microbial infections or tissue damage. VON ANDRIAN: They do not work like any of the traditional adjuvants, but they seem to have a direct effect on B cells.