Diabetes, broken capillaries, broken skin, bruising, impetigo, skin diseases and disorders. Unlike Retin A which thins the skin and comprises an acid type of Vitamin A. Environ’s vitamin A merchandise help to thicken the skin’s dermis layers, subsequently helping tremendously with aging skin, solar injury, pigmentation, and acne. This site comprises links to web sites to which our Privacy Policy does not apply. The skin crease as a fixed and everlasting line, based on their histology, is expounded to connective tissue attachments with the underlying structures or extensions of the underlying muscle fibers within the dermis of the crease site. The skin fold is characterized by skin redundancy that's responsible partly, typically in combination with connective tissue attachments, for the skin crease. Within the literature, when referring to a skin crease, there may be variation of terms used apart from "crease", equivalent to "fold" and "sulcus", however these terms do not precisely reflect their histology structure nor their function. Anatomical folds can be present in other structures and tissues besides the skin, such because the ileocecal fold beneath the terminal ileum of the cecum.