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Henkel T, Brunne RM, Mьller H (1999) Statistical investigation into the structural complementarity of purely natural solutions and artificial compounds. Gaisser S, Kellenberger L, Kaja AL, Weston AJ, Lill RE, Wirtz G, Kendrew SG, Low L, Sheridan RM, Wilkinson B, Galloway IS, Stutzman-Engwall K, McArthur HA, Staunton J, Leadlay PF (2003) Direct creation of ivermectin-like medications just after domain trade in the avermectin polyketide synthase of Streptomyces avermitilis ATCC31272. Gaisser S, Reather J, Wirtz G, Kellenberger L, Staunton J, Leadlay PF (2000) A described technique for hybrid macrolide biosynthesis in Saccharopolyspora erythraea. Cropp TA, Wilson DJ, Reynolds KA (2000) Identification of a cyclohexylcarbonyl CoA biosynthetic gene cluster and application in the generation of doramectin. Decker H, Haag S (1995) Cloning and characterization of a polyketide synthase gene from Streptomyces fradiae Tь2717, which carries the genes for biosynthesis of the angucycline antibiotic urdamycin A and a gene in all probability concerned in its oxygenation. Bate N, Cundliffe E (1999) The mycinose-biosynthetic genes of Streptomyces fradiae, producer of tylosin. Khosla C, Gokhale R, Jacobsen JR, Cane DE (1999) Tolerance and specificity of polyketide synthases. Del Vecchio F, Petkovic H, Kendrew SG, Low L, Wilkinson B, Lill R, Cortes J, Rudd BA, Staunton J, Leadlay PF (2003) Active-website residue, domain and module swaps in modular polyketide synthases.



Donadio S, Sosio M (2003) Strategies for combinatorial biosynthesis with modular polyketide synthases. Jacobsen JR, Hutchinson CR, Cane DE, Khosla C (1997) Precursor directed biosynthesis of novel erythromycin analogs by an engineered polyketide synthase. Frykman S, Leaf T, Carreras C, Licari P (2001) Precursor-directed output of erythromycin analogs by Saccharopolyspora erythraea. Chung L, Liu L, Patel S, Carney JR, Reeves CD (2001) Deletion of rap-QONML from the rapamycin gene cluster of Streptomyces hygroscopicus offers output of the 16-O-desmethyl-27-desmethoxy analog. Inouye M, Takada Y, Muto N, Beppu T, Horinouchi S (1994) Characterization and expression of a P-450-like mycinamicin biosynthesis gene making use of a novel Micromonospora-Escherichia coli shuttle cosmid vector. Recent reports have found identical premiums of crossover (referred to as polymorphism) employing formal records coupled with cure and assessment files. 27, has been making use of cam web sites for two yrs. Hopwood DA (1999) Forty yrs of genetics with Streptomyces: from in vivo as a result of in vitro to in silico.



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