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This smooth muscle mass peace causes vasodilation and enhanced inflow of bloodstream in to the spongy muscle associated with the penis, leading to a hardon. Robert F. Furchgott, Ferid Murad, and Louis Ignarro obtained the Nobel reward in Physiology or Medicine in 1998 for their separate research associated with metabolic pathway of nitric oxide in smooth muscle mass vasodilation. Pfizer originally discovered the medicine in 1989 while finding a treatment for heart-Related Web Page chest area pain.

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